Capability of a Process
The capability of a process to produce products that meet the required criteria.
Chemistry, Manufacturing and Control (CMC)
The various procedures used to assess the physical and chemical characteristics of drug products, and to ensure their quality and consistency during manufacturing.
Clinical Trial Report / Clinical Study Report
The administration of two or more drugs together.
Clean Zone
A local spatial structure which is constructed and used to minimize entry, generation and retention of particles within that zone.
Capping
The first modification made to transcribed RNA and takes place co-transcriptionally in the nucleus as soon as the first 25–30 nucleotides are incorporated into the transcript.
Chickenpox
An illness caused by the varicella-zoster virus characterized by an itchy rash with small, fluid-filled blisters.
Clinical Practice Guideline (CPG)
Statements that include recommendations intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options.
Capsid
The protein shell of a virus, enclosing its genetic material.
Chiral
Asymmetric in such a way that the structure and its mirror image are not superimposable.
Capsomere
The capsomere is a subunit of the capsid, an outer covering of protein that protects the genetic material of a virus. Capsomeres self-assemble to form the capsid.
Chromatography
A laboratory technique for the separation of a mixture into its components. Chemical mixture carried by a liquid or gas is separated into components as a result of differential distribution of the solutes as they flow around or over a stationary liquid or solid phase.
Capsule
A polysaccharide layer that lies outside the cell envelope of bacteria.
Chronic health condition
A health-related state (e.g., cancer, asthma) that lasts for a long period of time.
Carcinogenicity
The ability or tendency of a chemical to induce tumors.
Cleaning Validation
A procedure of establishing documented evidence that cleaning processes for manufacturing equipment prevents product contamination.
Carry-over Effect
Any effect from a previous experimental intervention that carries over onto a period after the experiment has been terminated and subjects are no longer experiencing the intervention.
Cleanroom
An engineered space that maintains a very low concentration of airborne particulates. It is well isolated, well controlled from contamination, and actively cleansed.